Product Description
Sirtuins in Health and Disease
Contains cutting-edge reviews of molecular biology, with this edition focusing on Sirtuins in Health and Disease
Weiping Zheng (Volume editor)
9780128122617
Hardback, published 27 January 2018
186 pages
22.9 x 15.2 x 1.9 cm, 0.43 kg
Sirtuins in Health and Disease, Volume 154 presents the reactions catalyzed by sirtuins in terms of their unique coenzyme NAD+-dependent catalytic mechanisms, the ways to elucidate these mechanisms, and the design of the inhibitory compounds against the sirtuin-catalyzed reactions as potential therapeutic agents for human diseases. Sections cover the concepts and chemical tools in sirtuin research, SIRT4 and SIRT7, the regulatory effects of NAD metabolic pathways on sirtuin activity, sirtuins as modifiers of Huntington\u2019s Disease (HD) pathology, parasite sirtuins as targets for novel chemotherapeutic agents, targeting sirtuins \u2013 substrate specificity and inhibitor design, and chemical probes in si]
Sirtuins in Health and Disease Zheng Hardback Academic Press Volume 154
Sirtuins in Health and Disease
Contains cutting-edge reviews of molecular biology, with this edition focusing on Sirtuins in Health and Disease
Weiping Zheng (Volume editor)
9780128122617
Hardback, published 27 January 2018
186 pages
22.9 x 15.2 x 1.9 cm, 0.43 kg
Sirtuins in Health and Disease, Volume 154 presents the reactions catalyzed by sirtuins in terms of their unique coenzyme NAD+-dependent catalytic mechanisms, the ways to elucidate these mechanisms, and the design of the inhibitory compounds against the sirtuin-catalyzed reactions as potential therapeutic agents for human diseases. Sections cover the concepts and chemical tools in sirtuin research, SIRT4 and SIRT7, the regulatory effects of NAD metabolic pathways on sirtuin activity, sirtuins as modifiers of Huntington\u2019s Disease (HD) pathology, parasite sirtuins as targets for novel chemotherapeutic agents, targeting sirtuins \u2013 substrate specificity and inhibitor design, and chemical probes in si]
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